Date & Location

June 12-14, 2018

Seminar room 3208, Bioteknia 1, Neulaniementie 2, Kuopio

Course description

This course will focus on current research in the topic of mitochondria and reactive oxygen species (ROS) signaling. Students will participate in lectures given by national and international experts in the field of mitochondria and ROS signaling and become familiar with advanced techniques to visualize and study mitochondria and ROS in multiple settings. The students also have the option to participate in practical demonstrations and prepare a poster presentation on their own research topic.

Lectures are open to all students, postdocs and personnel. Maximum participant amount to the lectures is 50 persons. For the workshop total of 10 students are enrolled.

For more info check Training school “Mitochondria and ROS signaling” webpage here.

 

Program

Lectures

Tuesday, 12 June 2018
10.00-10.15 Opening the course: Rashid Giniatullin and Tarja Malm
10.15-11.00 Mitochondria as generators of ROS. Andrey Abramov (UCL, London)
11.00-11.45 ROS induction of ALS IGGs. Pavle Andjus (Belgrade)
11.45-12.00 Sponsor talk
12.00-13.00 Lunch
13.00-13.45 Mitochondrial ROS signaling in heart development. Jaakko Pohjoismäki (Joensuu)
13.45-14.30 Compartmentalization of ROS signalling, Pasi Tavi (UEF)
14.30-15.00 Coffee
15.00-15.45 The role Nrf2 and downstream enzymes in prevention of the oxidative stress. Anna-Liisa Levonen (UEF)
15.45-16.30 Ferroptosis, a new form of cell death associated with accumulation of lipid peroxides. Gundars Goldsteins (UEF)
16.30-16.50 Junior leaders talk. Mitochondrial ROS in oxygen sensing and regulation of breathing. Plamena Angelova (UCL, London)
16.50-18.00 posters and short presentations of students
19.00 Get together
 

Wednesday, 13 June 2018

09.00-09.45 Effects of physical  exercise against oxidative stress and aberrant redox regulation  in ER stress. Mustafa Atalay (UEF)
09.45-10.15 Neuroprotective effects of Nrf2 in neurodegeneration. Antonio Cuadrado (Madrid)
10.15-10.45 Coffee
10.45-11.00 Sponsor talk
11.00-11.45 REDOX control in sensory and motor neurons. Rashid Giniatullin (UEF)
11.45-12.30 Transmitophagy: Novel Transcellular Means for Degradation of Mitochondria. Katja Kanninen (UEF)
12.30-13.30 Lunch
13.30-14.15 Two-photon imaging of mitochondria fragmentation in stroke and brain injury. Evgeny Pryazhnikov (Helsinki)
14.15-15.00 Imaging ROS with FACS. Igor Kudryavtsev (St-Petersburg)
15.00-15.30 Junior leaders talk. Mitochondrial ROS determine glutamate signal transduction of frontotemporal dementia. Noemi Esteras Gallego, (UCL, London)
15.30-16.15 Mechanisms of oxidative stress and neuroinflammation triggered by microglia. Tarja Malm (UEF)
16.15-16.45 Coffee
16.45-17.30 Open discussion. Topic TBA
17.30-18.30 Posters and short presentations of students

Demonstrations

Thursday, 14 June 2018
09.00-12.30 Laboratory demonstrations:
Imaging ROS with Flow cytometry
Organized by group of Dr. Tarja Malm (UEF)
12.30-13.30 Lunch
13.30-15.00 Laboratory demonstrations:
Imaging of ROS in neurons and cell lines with pharmacological and genetically encoded ROS sensors
Organized by Prof. Rashid Giniatullin (UEF)

 

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